PDB 5dos

PDB Information

PDB5DOS
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Allosteric modulation of AURKA kinase activity by a small-molecule inhibitor of its protein-protein interaction with TPX2.
Janecek, M., Rossmann, M., Sharma, P., Emery, A., Huggins, D.J., Stockwell, S.R., Stokes, J.E., Tan, Y.S., Almeida, E.G., Hardwick, B., Narvaez, A.J., Hyvonen, M., Spring, D.R., McKenzie, G.J., Venkitaraman, A.R.
Sci Rep
HeaderTransferase
Released2015-09-11
Resolution2.980
CATH Insert Date07 Aug, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5dosA01 01 Sep, 2016 3.30.200.20 Assigned
5dosA02 01 Sep, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A