PDB Information

PDB5DG5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Altiratinib Inhibits Tumor Growth, Invasion, Angiogenesis, and Microenvironment-Mediated Drug Resistance via Balanced Inhibition of MET, TIE2, and VEGFR2.
Smith, B.D., Kaufman, M.D., Leary, C.B., Turner, B.A., Wise, S.C., Ahn, Y.M., Booth, R.J., Caldwell, T.M., Ensinger, C.L., Hood, M.M., Lu, W.P., Patt, T.W., Patt, W.C., Rutkoski, T.J., Samarakoon, T., Telikepalli, H., Vogeti, L., Vogeti, S., Yates, K.M., Chun, L., Stewart, L.J., Clare, M., Flynn, D.L.
Mol.Cancer Ther.
HeaderTransferase/Transferase Inhibitor
Released2015-08-27
Resolution2.600
CATH Insert Date02 Oct, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 03 Oct, 2016 Chopped
B 03 Oct, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5dg5A01 07 Oct, 2016 3.30.200.20 Assigned
5dg5A02 07 Oct, 2016 1.10.510.10 Assigned
5dg5B01 06 Oct, 2016 3.30.200.20 Assigned
5dg5B02 06 Oct, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
P08581 MET_HUMAN Homo sapiens Hepatocyte growth factor receptor
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