PDB Information

PDB5DE1
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
New IDH1 mutant inhibitors for treatment of acute myeloid leukemia.
Okoye-Okafor, U.C., Bartholdy, B., Cartier, J., Gao, E.N., Pietrak, B., Rendina, A.R., Rominger, C., Quinn, C., Smallwood, A., Wiggall, K.J., Reif, A.J., Schmidt, S.J., Qi, H., Zhao, H., Joberty, G., Faelth-Savitski, M., Bantscheff, M., Drewes, G., Duraiswami, C., Brady, P., Groy, A., Narayanagari, S.R., Antony-Debre, I., Mitchell, K., Wang, H.R., Kao, Y.R., Christopeit, M., Carvajal, L., Barreyro, L., Paietta, E., Makishima, H., Will, B., Concha, N., Adams, N.D., Schwartz, B., McCabe, M.T., Maciejewski, J., Verma, A., Steidl, U.
Nat.Chem.Biol.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-08-25
Resolution2.250
CATH Insert Date18 Oct, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Oct, 2015 Chopped
B 19 Oct, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5de1A00 01 Nov, 2015 3.40.718.10 Assigned
5de1B00 01 Nov, 2015 3.40.718.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
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