PDB Information

PDB5D41
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
Jia, Y., Yun, C.H., Park, E., Ercan, D., Manuia, M., Juarez, J., Xu, C., Rhee, K., Chen, T., Zhang, H., Palakurthi, S., Jang, J., Lelais, G., DiDonato, M., Bursulaya, B., Michellys, P.Y., Epple, R., Marsilje, T.H., McNeill, M., Lu, W., Harris, J., Bender, S., Wong, K.K., Janne, P.A., Eck, M.J.
Nature
HeaderTransferase/Transferase Inhibitor
Released2015-08-07
Resolution2.310
CATH Insert Date19 Jun, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped
B 20 Jun, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5d41A01 13 Jul, 2016 3.30.200.20 Assigned
5d41A02 13 Jul, 2016 1.10.510.10 Assigned
5d41B01 13 Jul, 2016 3.30.200.20 Assigned
5d41B02 13 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor
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