PDB Information

PDB5CUS
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Inhibition of ErbB3 by a monoclonal antibody that locks the extracellular domain in an inactive configuration.
Lee, S., Greenlee, E.B., Amick, J.R., Ligon, G.F., Lillquist, J.S., Natoli, E.J., Hadari, Y., Alvarado, D., Schlessinger, J.
Proc.Natl.Acad.Sci.USA
HeaderTransferase
Released2015-07-25
Resolution3.200
CATH Insert Date25 Oct, 2015

PDB Images (33)

PDB Prints

PDB Chains (12)

Chain ID Date inserted into CATH CATH Status
A 26 Oct, 2015 Holding pen
B 26 Oct, 2015 Chopped
C 26 Oct, 2015 Domchop review
D 26 Oct, 2015 Holding pen
H 26 Oct, 2015 Chopped
I 26 Oct, 2015 Chopped
J 26 Oct, 2015 Chopped
K 26 Oct, 2015 Chopped
L 26 Oct, 2015 Chopped
M 26 Oct, 2015 Chopped
N 26 Oct, 2015 Chopped
O 26 Oct, 2015 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
5cusB01 25 Jan, 2018 3.80.20.20 Assigned
5cusB02 25 Jan, 2018 2.10.220.10 Assigned
5cusB03 25 Jan, 2018 3.80.20.20 Assigned
5cusB04 25 Jan, 2018 2.10.220.10 Assigned
5cusH01 01 Nov, 2015 2.60.40.10 Assigned
5cusH02 01 Nov, 2015 2.60.40.10 Assigned
5cusI01 01 Nov, 2015 2.60.40.10 Assigned
5cusI02 01 Nov, 2015 2.60.40.10 Assigned
5cusJ01 01 Nov, 2015 2.60.40.10 Assigned
5cusJ02 01 Nov, 2015 2.60.40.10 Assigned
5cusK01 01 Nov, 2015 2.60.40.10 Assigned
5cusK02 01 Nov, 2015 2.60.40.10 Assigned
5cusL01 05 Jul, 2016 2.60.40.10 Assigned
5cusL02 05 Jul, 2016 2.60.40.10 Assigned
5cusM01 05 Jul, 2016 2.60.40.10 Assigned
5cusM02 05 Jul, 2016 2.60.40.10 Assigned
5cusN01 05 Jul, 2016 2.60.40.10 Assigned
5cusN02 05 Jul, 2016 2.60.40.10 Assigned
5cusO01 05 Jul, 2016 2.60.40.10 Assigned
5cusO02 05 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3
P21860 ERBB3_HUMAN Homo sapiens Receptor tyrosine-protein kinase erbB-3