PDB 5crm

PDB Information

PDB5CRM
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
Xue, X., Zhang, Y., Liu, Z., Song, M., Xing, Y., Xiang, Q., Wang, Z., Tu, Z., Zhou, Y., Ding, K., Xu, Y.
J.Med.Chem.
HeaderSignaling Protein/Inhibitor
Released2015-07-23
Resolution1.990
CATH Insert Date10 Apr, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5crmA01 05 May, 2016 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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