PDB Information

PDB5CEI
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Development of a Potent, Specific CDK8 Kinase Inhibitor Which Phenocopies CDK8/19 Knockout Cells.
Koehler, M.F., Bergeron, P., Blackwood, E.M., Bowman, K., Clark, K.R., Firestein, R., Kiefer, J.R., Maskos, K., McCleland, M.L., Orren, L., Salphati, L., Schmidt, S., Schneider, E.V., Wu, J., Beresini, M.H.
Acs Med.Chem.Lett.
HeaderTranscription/Transferase/Inhibitor
Released2015-07-06
Resolution2.240
CATH Insert Date10 Apr, 2016

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
5ceiA01 05 May, 2016 3.30.200.20 Assigned
5ceiA02 05 May, 2016 1.10.510.10 Assigned
5ceiB01 05 May, 2016 1.10.472.10 Assigned
5ceiB02 05 May, 2016 1.10.472.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P49336 CDK8_HUMAN Homo sapiens Cyclin-dependent kinase 8
P24863 CCNC_HUMAN Homo sapiens Cyclin-C