PDB 5c2e

PDB Links
Overview

PDB Information

PDB	5C2E
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis. Shipe, W.D., Sharik, S.S., Barrow, J.C., McGaughey, G.B., Theberge, C.R., Uslaner, J.M., Yan, Y., Renger, J.J., Smith, S.M., Coleman, P.J., Cox, C.D. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-06-15
Resolution	2.100
CATH Insert Date	20 Dec, 2015

PDB Images (5)

Image of CATH 5c2e

5c2e

PDB 5c2e

Image of CATH 5c2eA

5c2eA

PDB Chain 5c2eA

Image of CATH 5c2eB

5c2eB

PDB Chain 5c2eB

Image of CATH 5c2eA00

5c2eA00

CATH Domain 5c2eA00

Image of CATH 5c2eB00

5c2eB00

CATH Domain 5c2eB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	21 Dec, 2015	Chopped
B	21 Dec, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
5c2eA00	05 Jan, 2016	1.10.1300.10	Assigned
5c2eB00	05 Jan, 2016	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A