PDB Information

PDB5C27
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Imidazotriazines: Spleen Tyrosine Kinase (Syk) Inhibitors Identified by Free-Energy Perturbation (FEP).
Lovering, F., Aevazelis, C., Chang, J., Dehnhardt, C., Fitz, L., Han, S., Janz, K., Lee, J., Kaila, N., McDonald, J., Moore, W., Moretto, A., Papaioannou, N., Richard, D., Ryan, M.S., Wan, Z.K., Thorarensen, A.
Chemmedchem
HeaderTransferase/Inhibitor
Released2015-06-15
Resolution2.150
CATH Insert Date18 Oct, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 19 Oct, 2015 Chopped
D 19 Oct, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5c27A01 01 Nov, 2015 3.30.200.20 Assigned
5c27A02 01 Nov, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P43405 KSYK_HUMAN Homo sapiens Tyrosine-protein kinase SYK
CATH-Gene3D is a Global Biodata Core Resource Learn more...