PDB Information

PDB5C0C
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Cole, D.K., Bulek, A.M., Dolton, G., Schauenberg, A.J., Szomolay, B., Rittase, W., Trimby, A., Jothikumar, P., Fuller, A., Skowera, A., Rossjohn, J., Zhu, C., Miles, J.J., Peakman, M., Wooldridge, L., Rizkallah, P.J., Sewell, A.K.
J.Clin.Invest.
HeaderImmune System
Released2015-06-12
Resolution1.970
CATH Insert Date15 May, 2016

PDB Images (25)

PDB Prints

PDB Chains (10)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped
C 16 May, 2016 Rejected
D 16 May, 2016 Chopped
E 16 May, 2016 Chopped
F 16 May, 2016 Chopped
G 16 May, 2016 Chopped
H 16 May, 2016 Rejected
I 16 May, 2016 Chopped
J 16 May, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5c0cA01 20 Oct, 2016 3.30.500.10 Assigned
5c0cA02 20 Oct, 2016 2.60.40.10 Assigned
5c0cB00 13 Jul, 2016 2.60.40.10 Assigned
5c0cD01 13 Jul, 2016 2.60.40.10 Assigned
5c0cD02 13 Jul, 2016 2.60.40.10 Assigned
5c0cE01 13 Jul, 2016 2.60.40.10 Assigned
5c0cE02 13 Jul, 2016 2.60.40.10 Assigned
5c0cF01 20 Oct, 2016 3.30.500.10 Assigned
5c0cF02 20 Oct, 2016 2.60.40.10 Assigned
5c0cG00 13 Jul, 2016 2.60.40.10 Assigned
5c0cI01 13 Jul, 2016 2.60.40.10 Assigned
5c0cI02 13 Jul, 2016 2.60.40.10 Assigned
5c0cJ01 12 Jul, 2016 2.60.40.10 Assigned
5c0cJ02 12 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
CATH-Gene3D is a Global Biodata Core Resource Learn more...