PDB 5c0a

PDB Information

PDB5C0A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Cole, D.K., Bulek, A.M., Dolton, G., Schauenberg, A.J., Szomolay, B., Rittase, W., Trimby, A., Jothikumar, P., Fuller, A., Skowera, A., Rossjohn, J., Zhu, C., Miles, J.J., Peakman, M., Wooldridge, L., Rizkallah, P.J., Sewell, A.K.
J.Clin.Invest.
HeaderImmune System
Released2015-06-12
Resolution2.460
CATH Insert Date15 May, 2016

PDB Images (25)

PDB Prints

PDB Chains (10)

Chain ID Date inserted into CATH CATH Status
A 16 May, 2016 Chopped
B 16 May, 2016 Chopped
C 16 May, 2016 Rejected
D 16 May, 2016 Chopped
E 16 May, 2016 Chopped
F 16 May, 2016 Chopped
G 16 May, 2016 Chopped
H 16 May, 2016 Rejected
I 16 May, 2016 Chopped
J 16 May, 2016 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
5c0aA01 20 Oct, 2016 3.30.500.10 Assigned
5c0aA02 20 Oct, 2016 2.60.40.10 Assigned
5c0aB00 13 Jul, 2016 2.60.40.10 Assigned
5c0aD01 13 Jul, 2016 2.60.40.10 Assigned
5c0aD02 13 Jul, 2016 2.60.40.10 Assigned
5c0aE01 13 Jul, 2016 2.60.40.10 Assigned
5c0aE02 13 Jul, 2016 2.60.40.10 Assigned
5c0aF01 19 Oct, 2016 3.30.500.10 Assigned
5c0aF02 19 Oct, 2016 2.60.40.10 Assigned
5c0aG00 13 Jul, 2016 2.60.40.10 Assigned
5c0aI01 13 Jul, 2016 2.60.40.10 Assigned
5c0aI02 13 Jul, 2016 2.60.40.10 Assigned
5c0aJ01 13 Jul, 2016 2.60.40.10 Assigned
5c0aJ02 13 Jul, 2016 2.60.40.10 Assigned

UniProtKB Entries (12)

Accession Gene ID Taxon Description
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4
A0A5B9 TRBC2_HUMAN Homo sapiens T cell receptor beta constant 2
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
A0A0B4J271 TVAL3_HUMAN Homo sapiens T cell receptor alpha variable 12-3
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
A0A0B4J2E0 TVBL4_HUMAN Homo sapiens T cell receptor beta variable 12-4
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
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