PDB 5ayg

PDB Information

PDB5AYG
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
SAR Exploration Guided by LE and Fsp(3): Discovery of a Selective and Orally Efficacious ROR gamma Inhibitor
Hirata, K., Kotoku, M., Seki, N., Maeba, T., Maeda, K., Hirashima, S., Sakai, T., Obika, S., Hori, A., Hase, Y., Yamaguchi, T., Katsuda, Y., Hata, T., Miyagawa, N., Arita, K., Nomura, Y., Asahina, K., Aratsu, Y., Kamada, M., Adachi, T., Noguchi, M., Doi, S., Crowe, P., Bradley, E., Steensma, R., Tao, H., Fenn, M., Babine, R., Li, X., Thacher, S., Hashimoto, H., Shiozaki, M.
Acs Med.Chem.Lett.
HeaderDna Binding Protein/Inhibitor
Released2015-08-20
Resolution2.600
CATH Insert Date10 Apr, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5aygA00 04 May, 2016 1.10.565.10 Assigned
5aygB00 04 May, 2016 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma