PDB 5aqs

PDB Information

PDB5AQS
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
A fragment-based approach applied to a highly flexible target: Insights and challenges towards the inhibition of HSP70 isoforms.
Jones, A.M., Westwood, I.M., Osborne, J.D., Matthews, T.P., Cheeseman, M.D., Rowlands, M.G., Jeganathan, F., Burke, R., Lee, D., Kadi, N., Liu, M., Richards, M., McAndrew, C., Yahya, N., Dobson, S.E., Jones, K., Workman, P., Collins, I., van Montfort, R.L.
Sci Rep
HeaderChaperone
Released2015-09-22
Resolution2.000
CATH Insert Date16 Oct, 2016

PDB Images (15)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 17 Oct, 2016 Chopped
B 17 Oct, 2016 Chopped
C 17 Oct, 2016 Chopped
D 17 Oct, 2016 Chopped

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
5aqsA01 25 Oct, 2016 3.30.420.40 Assigned
5aqsA02 25 Oct, 2016 3.30.30.30 Assigned
5aqsA03 25 Oct, 2016 3.30.420.40 Assigned
5aqsA04 25 Oct, 2016 3.90.640.10 Assigned
5aqsB00 22 Oct, 2016 1.20.58.120 Assigned
5aqsC01 25 Oct, 2016 3.30.420.40 Assigned
5aqsC02 25 Oct, 2016 3.30.30.30 Assigned
5aqsC03 25 Oct, 2016 3.30.420.40 Assigned
5aqsC04 25 Oct, 2016 3.90.640.10 Assigned
5aqsD00 22 Oct, 2016 1.20.58.120 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein
Q99933 BAG1_HUMAN Homo sapiens BAG family molecular chaperone regulator 1
P11142 HSP7C_HUMAN Homo sapiens Heat shock cognate 71 kDa protein