PDB 5aph

PDB Information

PDB5APH
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH 17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma.
Olsson, R.I., Xue, Y., von Berg, S., Aagaard, A., McPheat, J., Hansson, E.L., Bernstrom, J., Hansson, P., Jirholt, J., Grindebacke, H., Leffler, A., Chen, R., Xiong, Y., Ge, H., Hansson, T.G., Narjes, F.
ChemMedChem
HeaderTranscription
Released2015-09-16
Resolution1.540
CATH Insert Date06 Dec, 2015

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Dec, 2015 Chopped
C 07 Dec, 2015 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5aphA00 05 Jan, 2016 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
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