PDB 5amn

PDB Information

PDB5AMN
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
The discovery of 2-substituted phenol quinazolines as potent RET kinase inhibitors with improved KDR selectivity.
Newton, R., Bowler, K.A., Burns, E.M., Chapman, P.J., Fairweather, E.E., Fritzl, S.J.R., Goldberg, K.M., Hamilton, N.M., Holt, S.V., Hopkins, G.V., Jones, S.D., Jordan, A.M., Lyons, A.J., Nikki March, H., McDonald, N.Q., Maguire, L.A., Mould, D.P., Purkiss, A.G., Small, H.F., Stowell, A.I.J., Thomson, G.J., Waddell, I.D., Waszkowycz, B., Watson, A.J., Ogilvie, D.J.
Eur J Med Chem
HeaderTransferase
Released2015-03-11
Resolution2.570
CATH Insert Date10 Apr, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5amnA01 03 May, 2016 3.30.200.20 Assigned
5amnA02 03 May, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P07949 RET_HUMAN Homo sapiens Proto-oncogene tyrosine-protein kinase receptor Ret