PDB Information

PDB5AGR
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceMYCOBACTERIUM TUBERCULOSIS
Primary Citation
Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium Tuberculosis that Target Leucyl-tRNA Synthetase.
Palencia, A., Li, X., Bu, W., Choi, W., Ding, C.Z., Easom, E.E., Feng, L., Hernandez, V., Houston, P., Liu, L., Meewan, M., Mohan, M., Rock, F.L., Sexton, H., Zhang, S., Zhou, Y., Wan, B., Wang, Y., Franzblau, S.G., Woolhiser, L., Gruppo, V., Lenaerts, A.J., O'Malley, T., Parish, T., Cooper, C.B., Waters, M.G., Ma, Z., Ioerger, T.R., Sacchettini, J.C., Rullas, J., Angulo-Barturen, I., Perez-Herran, E., Mendoza, A., Barros, D., Cusack, S., Plattner, J.J., Alley, M.R.K.
Antimicrob.Agents Chemother.
HeaderLigase
Released2015-02-03
Resolution1.300
CATH Insert Date10 Apr, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
5agrA00 03 May, 2016 3.90.740.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P9WFV1 SYL_MYCTU Mycobacterium tuberculosis H37Rv Leucine--tRNA ligase
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