PDB 5aa8

PDB Information

PDB5AA8
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Resensitization to Crizotinib by the Lorlatinib Alk Resistance Mutation L1198F.
Shaw, A.T., Friboulet, L., Leshchiner, I., Gainor, J.F., Bergqvist, S., Brooun, A., Burke, B.J., Deng, Y., Liu, W., Dardaei, L., Frias, R.L., Schultz, K.R., Logan, J., James, L.P., Smeal, T., Timofeevski, S., Katayama, R., Iafrate, A.J., Le, L., Mctigue, M., Getz, G., Johnson, T.W., Engelman, J.A.
N.Engl.J.Med.
HeaderTransferase
Released2015-07-23
Resolution1.860
CATH Insert Date19 Jun, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Jun, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5aa8A01 12 Jul, 2016 3.30.200.20 Assigned
5aa8A02 12 Jul, 2016 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor
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