PDB 5a8x

PDB Information

PDB5A8X
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Potent and Selective Human Neutrophil Elastase Inhibitors with Novel Equatorial Ring Topology: in vivo Efficacy of the Polar Pyrimidopyridazine BAY-8040 in a Pulmonary Arterial Hypertension Rat Model.
von Nussbaum, F., Li, V.M., Meibom, D., Anlauf, S., Bechem, M., Delbeck, M., Gerisch, M., Harrenga, A., Karthaus, D., Lang, D., Lustig, K., Mittendorf, J., Schafer, M., Schafer, S., Schamberger, J.
ChemMedChem
HeaderHydrolase
Released2015-07-17
Resolution2.230
CATH Insert Date14 Aug, 2016

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 15 Aug, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5a8xA01 01 Sep, 2016 2.40.10.10 Assigned
5a8xA02 01 Sep, 2016 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P08246 ELNE_HUMAN Homo sapiens Neutrophil elastase
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