PDB Information

PDB5A3N
MethodX-RAY DIFFRACTION
Host OrganismSPODOPTERA FRUGIPERDA
Gene SourceHOMO SAPIENS
Primary Citation
Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.
Tumber, A., Nuzzi, A., Hookway, E.S., Hatch, S.B., Velupillai, S., Johansson, C., Kawamura, A., Savitsky, P., Yapp, C., Szykowska, A., Wu, N., Bountra, C., Strain-Damerell, C., Burgess-Brown, N.A., Ruda, G.F., Fedorov, O., Munro, S., England, K.S., Nowak, R.P., Schofield, C.J., La Thangue, N.B., Pawlyn, C., Davies, F., Morgan, G., Athanasou, N., Muller, S., Oppermann, U., Brennan, P.E.
Cell Chem Biol
HeaderOxidoreductase
Released2015-06-02
Resolution2.000
CATH Insert Date26 Jul, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 27 Jul, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
5a3nA01 21 Jul, 2016 2.60.120.650 Assigned
5a3nA02 21 Jul, 2016 Holding pen

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UGL1 KDM5B_HUMAN Homo sapiens Lysine-specific demethylase 5B