PDB Information

PDB4ZZI
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Crystallographic structure of a small molecule SIRT1 activator-enzyme complex.
Dai, H., Case, A.W., Riera, T.V., Considine, T., Lee, J.E., Hamuro, Y., Zhao, H., Jiang, Y., Sweitzer, S.M., Pietrak, B., Schwartz, B., Blum, C.A., Disch, J.S., Caldwell, R., Szczepankiewicz, B., Oalmann, C., Yee Ng, P., White, B.H., Casaubon, R., Narayan, R., Koppetsch, K., Bourbonais, F., Wu, B., Wang, J., Qian, D., Jiang, F., Mao, C., Wang, M., Hu, E., Wu, J.C., Perni, R.B., Vlasuk, G.P., Ellis, J.L.
Nat Commun
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-22
Resolution2.730
CATH Insert Date26 Jul, 2015

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 27 Jul, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4zziA01 21 Jul, 2016 Write scan list
4zziA02 21 Jul, 2016 3.40.50.1220 Assigned
4zziA03 21 Jul, 2016 3.30.1600.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q96EB6 SIR1_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-1