PDB Information

PDB4ZZ2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
6-Substituted Pyrrolo[2,3-d]pyrimidine Thienoyl Regioisomers as Targeted Antifolates for Folate Receptor alpha and the Proton-Coupled Folate Transporter in Human Tumors.
Wang, L., Wallace, A., Raghavan, S., Deis, S.M., Wilson, M.R., Yang, S., Polin, L., White, K., Kushner, J., Orr, S., George, C., O'Connor, C., Hou, Z., Mitchell-Ryan, S., Dann, C.E., Matherly, L.H., Gangjee, A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-05-22
Resolution1.450
CATH Insert Date27 Dec, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 28 Dec, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4zz2A00 30 Nov, 2016 3.40.50.170 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P22102 PUR2_HUMAN Homo sapiens Trifunctional purine biosynthetic protein adenosine-3