PDB 4zyi

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Overview

PDB Information

PDB	4ZYI
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors. Holzer, P., Masuya, K., Furet, P., Kallen, J., Valat-Stachyra, T., Ferretti, S., Berghausen, J., Bouisset-Leonard, M., Buschmann, N., Pissot-Soldermann, C., Rynn, C., Ruetz, S., Stutz, S., Chene, P., Jeay, S., Gessier, F. J.Med.Chem.
Header	Cell Cycle
Released	2015-05-21
Resolution	1.670
CATH Insert Date	16 Aug, 2015

PDB Images (3)

Image of CATH 4zyi

4zyi

PDB 4zyi

Image of CATH 4zyiA

4zyiA

PDB Chain 4zyiA

Image of CATH 4zyiA00

4zyiA00

CATH Domain 4zyiA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	17 Aug, 2015	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4zyiA00	20 Mar, 2016	1.10.245.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q00987	MDM2_HUMAN	Homo sapiens	E3 ubiquitin-protein ligase Mdm2