PDB 4zsp

PDB Information

PDB4ZSP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Preparation and biological evaluation of conformationally constrained BACE1 inhibitors.
Winneroski, L.L., Schiffler, M.A., Erickson, J.A., May, P.C., Monk, S.A., Timm, D.E., Audia, J.E., Beck, J.P., Boggs, L.N., Borders, A.R., Boyer, R.D., Brier, R.A., Hudziak, K.J., Klimkowski, V.J., Garcia Losada, P., Mathes, B.M., Stout, S.L., Watson, B.M., Mergott, D.J.
Bioorg.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-05-13
Resolution1.910
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4zspA01 27 Jul, 2015 2.40.70.10 Assigned
4zspA02 27 Jul, 2015 2.40.70.10 Assigned
4zspB01 27 Jul, 2015 2.40.70.10 Assigned
4zspB02 27 Jul, 2015 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1