PDB Information

PDB4ZJS
MethodX-RAY DIFFRACTION
Host OrganismHomo sapiens
Gene SourceHomo sapiens
Primary Citation
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
Luo, J., Taylor, P., Losen, M., de Baets, M.H., Shelton, G.D., Lindstrom, J.
J. Neurosci.
HeaderImmune System
Released2015-04-29
Resolution2.230
CATH Insert Date28 Jun, 2015

PDB Images (11)

PDB Prints

PDB Chains (5)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4zjsA00 27 Jul, 2015 2.70.170.10 Assigned
4zjsB00 27 Jul, 2015 2.70.170.10 Assigned
4zjsC00 27 Jul, 2015 2.70.170.10 Assigned
4zjsD00 27 Jul, 2015 2.70.170.10 Assigned
4zjsE00 27 Jul, 2015 2.70.170.10 Assigned

UniProtKB Entries (10)

Accession Gene ID Taxon Description
P02708 ACHA_HUMAN Homo sapiens Acetylcholine receptor subunit alpha
P02708 ACHA_HUMAN Homo sapiens Acetylcholine receptor subunit alpha
P02708 ACHA_HUMAN Homo sapiens Acetylcholine receptor subunit alpha
Q8WSF8 Q8WSF8_APLCA Aplysia californica Soluble acetylcholine receptor
Q8WSF8 Q8WSF8_APLCA Aplysia californica Soluble acetylcholine receptor
Q8WSF8 Q8WSF8_APLCA Aplysia californica Soluble acetylcholine receptor
Q8WSF8 Q8WSF8_APLCA Aplysia californica Soluble acetylcholine receptor
P02708 ACHA_HUMAN Homo sapiens Acetylcholine receptor subunit alpha
Q8WSF8 Q8WSF8_APLCA Aplysia californica Soluble acetylcholine receptor
P02708 ACHA_HUMAN Homo sapiens Acetylcholine receptor subunit alpha