PDB Information

PDB4ZIL
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceMycobacterium tuberculosis (H37Rv)
Primary Citation
The Redox State Regulates the Conformation of Rv2466c to Activate the Antitubercular Prodrug TP053.
Albesa-Jove, D., Comino, N., Tersa, M., Mohorko, E., Urresti, S., Dainese, E., Chiarelli, L.R., Pasca, M.R., Manganelli, R., Makarov, V., Riccardi, G., Svergun, D.I., Glockshuber, R., Guerin, M.E.
J.Biol.Chem.
HeaderOxidoreductase
Released2015-04-28
Resolution1.510
CATH Insert Date29 Nov, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4zilA00 03 Dec, 2015 3.40.30.10 Assigned
4zilB00 02 Dec, 2015 3.40.30.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O53193 TRLR_MYCTU Mycobacterium tuberculosis H37Rv Thioredoxin-like reductase Rv2466c
O53193 TRLR_MYCTU Mycobacterium tuberculosis H37Rv Thioredoxin-like reductase Rv2466c