PDB 4z1l

PDB Links
Overview

PDB Information

PDB	4Z1L
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	A Minimal beta-Lactone Fragment for Selective beta 5c or beta 5i Proteasome Inhibitors. Groll, M., Korotkov, V.S., Huber, E.M., de Meijere, A., Ludwig, A. Angew.Chem.Int.Ed.Engl.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-03-27
Resolution	3.000
CATH Insert Date	28 Jun, 2015

PDB Images (57)

4z1l

PDB 4z1l

4z1la

PDB Chain 4z1la

4z1lA

PDB Chain 4z1lA

4z1lb

PDB Chain 4z1lb

4z1lB

PDB Chain 4z1lB

4z1lC

PDB Chain 4z1lC

4z1lD

PDB Chain 4z1lD

4z1lE

PDB Chain 4z1lE

4z1lF

PDB Chain 4z1lF

4z1lG

PDB Chain 4z1lG

4z1lH

PDB Chain 4z1lH

4z1lI

PDB Chain 4z1lI

4z1lJ

PDB Chain 4z1lJ

4z1lK

PDB Chain 4z1lK

4z1lL

PDB Chain 4z1lL

4z1lM

PDB Chain 4z1lM

4z1lN

PDB Chain 4z1lN

4z1lO

PDB Chain 4z1lO

4z1lP

PDB Chain 4z1lP

4z1lQ

PDB Chain 4z1lQ

4z1lR

PDB Chain 4z1lR

4z1lS

PDB Chain 4z1lS

4z1lT

PDB Chain 4z1lT

4z1lU

PDB Chain 4z1lU

4z1lV

PDB Chain 4z1lV

4z1lW

PDB Chain 4z1lW

4z1lX

PDB Chain 4z1lX

4z1lY

PDB Chain 4z1lY

4z1lZ

PDB Chain 4z1lZ

4z1la00

CATH Domain 4z1la00

4z1lA00

CATH Domain 4z1lA00

4z1lb00

CATH Domain 4z1lb00

4z1lB00

CATH Domain 4z1lB00

4z1lC00

CATH Domain 4z1lC00

4z1lD00

CATH Domain 4z1lD00

4z1lE00

CATH Domain 4z1lE00

4z1lF00

CATH Domain 4z1lF00

4z1lG00

CATH Domain 4z1lG00

4z1lH00

CATH Domain 4z1lH00

4z1lI00

CATH Domain 4z1lI00

4z1lJ00

CATH Domain 4z1lJ00

4z1lK00

CATH Domain 4z1lK00

4z1lL00

CATH Domain 4z1lL00

4z1lM00

CATH Domain 4z1lM00

4z1lN00

CATH Domain 4z1lN00

4z1lO00

CATH Domain 4z1lO00

4z1lP00

CATH Domain 4z1lP00

4z1lQ00

CATH Domain 4z1lQ00

4z1lR00

CATH Domain 4z1lR00

4z1lS00

CATH Domain 4z1lS00

4z1lT00

CATH Domain 4z1lT00

4z1lU00

CATH Domain 4z1lU00

4z1lV00

CATH Domain 4z1lV00

4z1lW00

CATH Domain 4z1lW00

4z1lX00

CATH Domain 4z1lX00

4z1lY00

CATH Domain 4z1lY00

4z1lZ00

CATH Domain 4z1lZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
b	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped
D	29 Jun, 2015	Chopped
E	29 Jun, 2015	Chopped
F	29 Jun, 2015	Chopped
G	29 Jun, 2015	Chopped
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4z1la00	27 Jul, 2015	3.60.20.10	Assigned
4z1lA00	27 Jul, 2015	3.60.20.10	Assigned
4z1lb00	27 Jul, 2015	3.60.20.10	Assigned
4z1lB00	27 Jul, 2015	3.60.20.10	Assigned
4z1lC00	27 Jul, 2015	3.60.20.10	Assigned
4z1lD00	27 Jul, 2015	3.60.20.10	Assigned
4z1lE00	27 Jul, 2015	3.60.20.10	Assigned
4z1lF00	27 Jul, 2015	3.60.20.10	Assigned
4z1lG00	27 Jul, 2015	3.60.20.10	Assigned
4z1lH00	27 Jul, 2015	3.60.20.10	Assigned
4z1lI00	27 Jul, 2015	3.60.20.10	Assigned
4z1lJ00	27 Jul, 2015	3.60.20.10	Assigned
4z1lK00	27 Jul, 2015	3.60.20.10	Assigned
4z1lL00	27 Jul, 2015	3.60.20.10	Assigned
4z1lM00	27 Jul, 2015	3.60.20.10	Assigned
4z1lN00	27 Jul, 2015	3.60.20.10	Assigned
4z1lO00	27 Jul, 2015	3.60.20.10	Assigned
4z1lP00	27 Jul, 2015	3.60.20.10	Assigned
4z1lQ00	27 Jul, 2015	3.60.20.10	Assigned
4z1lR00	27 Jul, 2015	3.60.20.10	Assigned
4z1lS00	27 Jul, 2015	3.60.20.10	Assigned
4z1lT00	27 Jul, 2015	3.60.20.10	Assigned
4z1lU00	27 Jul, 2015	3.60.20.10	Assigned
4z1lV00	27 Jul, 2015	3.60.20.10	Assigned
4z1lW00	27 Jul, 2015	3.60.20.10	Assigned
4z1lX00	27 Jul, 2015	3.60.20.10	Assigned
4z1lY00	27 Jul, 2015	3.60.20.10	Assigned
4z1lZ00	27 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5