PDB Information

PDB4YZC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity.
Concha, N.O., Smallwood, A., Bonnette, W., Totoritis, R., Zhang, G., Federowicz, K., Yang, J., Qi, H., Chen, S., Campobasso, N., Choudhry, A.E., Shuster, L.E., Evans, K.A., Ralph, J., Sweitzer, S., Heerding, D.A., Buser, C.A., Su, D.S., DeYoung, M.P.
Mol.Pharmacol.
HeaderTransferase/Transferase Inhibitor
Released2015-03-24
Resolution2.490
CATH Insert Date29 Nov, 2015

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4yzcA01 03 Dec, 2015 3.30.200.20 Assigned
4yzcA02 03 Dec, 2015 1.10.510.10 Assigned
4yzcA03 03 Dec, 2015 1.20.1440.180 Assigned
4yzcB01 02 Dec, 2015 3.30.200.20 Assigned
4yzcB02 02 Dec, 2015 1.10.510.10 Assigned
4yzcB03 02 Dec, 2015 1.20.1440.180 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1