PDB Information

PDB4YZ9
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1 alpha Endoribonuclease Activity.
Concha, N.O., Smallwood, A., Bonnette, W., Totoritis, R., Zhang, G., Federowicz, K., Yang, J., Qi, H., Chen, S., Campobasso, N., Choudhry, A.E., Shuster, L.E., Evans, K.A., Ralph, J., Sweitzer, S., Heerding, D.A., Buser, C.A., Su, D.S., DeYoung, M.P.
Mol.Pharmacol.
HeaderTransferase/Transferase Inhibitor
Released2015-03-24
Resolution2.460
CATH Insert Date29 Nov, 2015

PDB Images (13)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 30 Nov, 2015 Chopped
B 30 Nov, 2015 Chopped
C 30 Nov, 2015 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
4yz9A01 03 Dec, 2015 3.30.200.20 Assigned
4yz9A02 03 Dec, 2015 1.10.510.10 Assigned
4yz9A03 03 Dec, 2015 1.20.1440.180 Assigned
4yz9B01 03 Dec, 2015 3.30.200.20 Assigned
4yz9B02 03 Dec, 2015 1.10.510.10 Assigned
4yz9B03 03 Dec, 2015 1.20.1440.180 Assigned
4yz9C01 03 Dec, 2015 3.30.200.20 Assigned
4yz9C02 03 Dec, 2015 1.10.510.10 Assigned
4yz9C03 03 Dec, 2015 1.20.1440.180 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1
O75460 ERN1_HUMAN Homo sapiens Serine/threonine-protein kinase/endoribonuclease IRE1