PDB Information

PDB4YYZ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli 'BL21-Gold(DE3)pLysS AG'
Gene SourceHomo sapiens
Primary Citation
Design of pyrozolo-pyrimidines as 11beta-HSD1 inhibitors through optimisation of molecular electrostatic potential.
Robb, G.R., Boyd, S., Davies, C.D., Dossiter, A.G., Goldberg, F.W., Kemmitt, P.D., Scott, J.S., Swales, J.G.
Medchemcomm
HeaderOxidoreductase
Released2015-03-24
Resolution3.200
CATH Insert Date10 Apr, 2016

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped
B 11 Apr, 2016 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4yyzA00 02 May, 2016 3.40.50.720 Assigned
4yyzB00 02 May, 2016 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845 DHI1_HUMAN Homo sapiens Corticosteroid 11-beta-dehydrogenase isozyme 1
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