PDB Information

PDB4YS7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Evolution and synthesis of novel orally bioavailable inhibitors of PDE10A.
Burdi, D.F., Campbell, J.E., Wang, J., Zhao, S., Zhong, H., Wei, J., Campbell, U., Shao, L., Herman, L., Koch, P., Jones, P.G., Hewitt, M.C.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2015-03-16
Resolution2.500
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4ys7A00 22 Jul, 2015 1.10.1300.10 Assigned
4ys7B00 22 Jul, 2015 1.10.1300.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233 PDE10_HUMAN Homo sapiens cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
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