PDB Information

PDB4YLJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
10-Iodo-11H-indolo[3,2-c]quinoline-6-carboxylic Acids Are Selective Inhibitors of DYRK1A.
Falke, H., Chaikuad, A., Becker, A., Loaec, N., Lozach, O., Abu Jhaisha, S., Becker, W., Jones, P.G., Preu, L., Baumann, K., Knapp, S., Meijer, L., Kunick, C.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2015-03-05
Resolution2.580
CATH Insert Date28 Jun, 2015

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4yljA01 22 Jul, 2015 3.30.200.20 Assigned
4yljA02 22 Jul, 2015 1.10.510.10 Assigned
4yljB01 22 Jul, 2015 3.30.200.20 Assigned
4yljB02 22 Jul, 2015 1.10.510.10 Assigned
4yljC01 22 Jul, 2015 3.30.200.20 Assigned
4yljC02 22 Jul, 2015 1.10.510.10 Assigned
4yljD01 22 Jul, 2015 3.30.200.20 Assigned
4yljD02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A
Q13627 DYR1A_HUMAN Homo sapiens Dual specificity tyrosine-phosphorylation-regulated kinase 1A