PDB 4yh3

PDB Information

PDB4YH3
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Discovery of a new chemical series of BRD4(1) inhibitors using protein-ligand docking and structure-guided design.
Duffy, B.C., Liu, S., Martin, G.S., Wang, R., Hsia, M.M., Zhao, H., Guo, C., Ellis, M., Quinn, J.F., Kharenko, O.A., Norek, K., Gesner, E.M., Young, P.R., McLure, K.G., Wagner, G.S., Lakshminarasimhan, D., White, A., Suto, R.K., Hansen, H.C., Kitchen, D.B.
Bioorg.Med.Chem.Lett.
HeaderProtein Binding
Released2015-02-26
Resolution1.600
CATH Insert Date10 Apr, 2016

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Apr, 2016 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4yh3A01 01 May, 2016 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O60885 BRD4_HUMAN Homo sapiens Bromodomain-containing protein 4
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