PDB 4yc9

PDB Information

PDB4YC9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor.
Palmer, W.S., Poncet-Montange, G., Liu, G., Petrocchi, A., Reyna, N., Subramanian, G., Theroff, J., Yau, A., Kost-Alimova, M., Bardenhagen, J.P., Leo, E., Shepard, H.E., Tieu, T.N., Shi, X., Zhan, Y., Zhao, S., Barton, M.C., Draetta, G., Toniatti, C., Jones, P., Geck Do, M., Andersen, J.N.
J.Med.Chem.
HeaderTranscription/Transcription Inhibitor
Released2015-02-19
Resolution1.820
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4yc9A01 22 Jul, 2015 3.30.40.10 Assigned
4yc9A02 22 Jul, 2015 1.20.920.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O15164 TIF1A_HUMAN Homo sapiens Transcription intermediary factor 1-alpha