PDB 4yax

PDB Links
Overview

PDB Information

PDB	4YAX
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. Palmer, W.S., Poncet-Montange, G., Liu, G., Petrocchi, A., Reyna, N., Subramanian, G., Theroff, J., Yau, A., Kost-Alimova, M., Bardenhagen, J.P., Leo, E., Shepard, H.E., Tieu, T.N., Shi, X., Zhan, Y., Zhao, S., Barton, M.C., Draetta, G., Toniatti, C., Jones, P., Geck Do, M., Andersen, J.N. J.Med.Chem.
Header	Transcription/Transcription Inhibitor
Released	2015-02-18
Resolution	2.250
CATH Insert Date	28 Jun, 2015

PDB Images (7)

Image of CATH 4yax

4yax

PDB 4yax

Image of CATH 4yaxA

4yaxA

PDB Chain 4yaxA

Image of CATH 4yaxB

4yaxB

PDB Chain 4yaxB

Image of CATH 4yaxA01

4yaxA01

CATH Domain 4yaxA01

Image of CATH 4yaxA02

4yaxA02

CATH Domain 4yaxA02

Image of CATH 4yaxB01

4yaxB01

CATH Domain 4yaxB01

Image of CATH 4yaxB02

4yaxB02

CATH Domain 4yaxB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4yaxA01	22 Jul, 2015	3.30.40.10	Assigned
4yaxA02	22 Jul, 2015	1.20.920.10	Assigned
4yaxB01	22 Jul, 2015	3.30.40.10	Assigned
4yaxB02	22 Jul, 2015	1.20.920.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O15164	TIF1A_HUMAN	Homo sapiens	Transcription intermediary factor 1-alpha
O15164	TIF1A_HUMAN	Homo sapiens	Transcription intermediary factor 1-alpha