PDB 4y8l

PDB Links
Overview

PDB Information

PDB	4Y8L
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors. Huber, E.M., de Bruin, G., Heinemeyer, W., Paniagua Soriano, G., Overkleeft, H.S., Groll, M. J.Am.Chem.Soc.
Header	Hydrolase/Hydrolase Inhibitor
Released	2015-02-16
Resolution	2.400
CATH Insert Date	28 Jun, 2015

PDB Images (61)

4y8l

PDB 4y8l

4y8la

PDB Chain 4y8la

4y8lA

PDB Chain 4y8lA

4y8lb

PDB Chain 4y8lb

4y8lB

PDB Chain 4y8lB

4y8lc

PDB Chain 4y8lc

4y8lC

PDB Chain 4y8lC

4y8ld

PDB Chain 4y8ld

4y8lD

PDB Chain 4y8lD

4y8le

PDB Chain 4y8le

4y8lE

PDB Chain 4y8lE

4y8lf

PDB Chain 4y8lf

4y8lF

PDB Chain 4y8lF

4y8lG

PDB Chain 4y8lG

4y8lH

PDB Chain 4y8lH

4y8lI

PDB Chain 4y8lI

4y8lJ

PDB Chain 4y8lJ

4y8lK

PDB Chain 4y8lK

4y8lL

PDB Chain 4y8lL

4y8lM

PDB Chain 4y8lM

4y8lN

PDB Chain 4y8lN

4y8lO

PDB Chain 4y8lO

4y8lP

PDB Chain 4y8lP

4y8lQ

PDB Chain 4y8lQ

4y8lR

PDB Chain 4y8lR

4y8lS

PDB Chain 4y8lS

4y8lT

PDB Chain 4y8lT

4y8lU

PDB Chain 4y8lU

4y8lV

PDB Chain 4y8lV

4y8lW

PDB Chain 4y8lW

4y8lX

PDB Chain 4y8lX

4y8lY

PDB Chain 4y8lY

4y8lZ

PDB Chain 4y8lZ

4y8la00

CATH Domain 4y8la00

4y8lA00

CATH Domain 4y8lA00

4y8lb00

CATH Domain 4y8lb00

4y8lB00

CATH Domain 4y8lB00

4y8lC00

CATH Domain 4y8lC00

4y8lD00

CATH Domain 4y8lD00

4y8lE00

CATH Domain 4y8lE00

4y8lF00

CATH Domain 4y8lF00

4y8lG00

CATH Domain 4y8lG00

4y8lH00

CATH Domain 4y8lH00

4y8lI00

CATH Domain 4y8lI00

4y8lJ00

CATH Domain 4y8lJ00

4y8lK00

CATH Domain 4y8lK00

4y8lL00

CATH Domain 4y8lL00

4y8lM00

CATH Domain 4y8lM00

4y8lN00

CATH Domain 4y8lN00

4y8lO00

CATH Domain 4y8lO00

4y8lP00

CATH Domain 4y8lP00

4y8lQ00

CATH Domain 4y8lQ00

4y8lR00

CATH Domain 4y8lR00

4y8lS00

CATH Domain 4y8lS00

4y8lT00

CATH Domain 4y8lT00

4y8lU00

CATH Domain 4y8lU00

4y8lV00

CATH Domain 4y8lV00

4y8lW00

CATH Domain 4y8lW00

4y8lX00

CATH Domain 4y8lX00

4y8lY00

CATH Domain 4y8lY00

4y8lZ00

CATH Domain 4y8lZ00

PDB Prints

PDB Chains (32)

Chain ID	Date inserted into CATH	CATH Status
a	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
b	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
c	29 Jun, 2015	Rejected
C	29 Jun, 2015	Chopped
d	29 Jun, 2015	Rejected
D	29 Jun, 2015	Chopped
e	29 Jun, 2015	Rejected
E	29 Jun, 2015	Chopped
f	29 Jun, 2015	Rejected
F	29 Jun, 2015	Chopped
G	29 Jun, 2015	Chopped
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4y8la00	22 Jul, 2015	3.60.20.10	Assigned
4y8lA00	22 Jul, 2015	3.60.20.10	Assigned
4y8lb00	22 Jul, 2015	3.60.20.10	Assigned
4y8lB00	22 Jul, 2015	3.60.20.10	Assigned
4y8lC00	22 Jul, 2015	3.60.20.10	Assigned
4y8lD00	22 Jul, 2015	3.60.20.10	Assigned
4y8lE00	22 Jul, 2015	3.60.20.10	Assigned
4y8lF00	22 Jul, 2015	3.60.20.10	Assigned
4y8lG00	22 Jul, 2015	3.60.20.10	Assigned
4y8lH00	22 Jul, 2015	3.60.20.10	Assigned
4y8lI00	22 Jul, 2015	3.60.20.10	Assigned
4y8lJ00	22 Jul, 2015	3.60.20.10	Assigned
4y8lK00	22 Jul, 2015	3.60.20.10	Assigned
4y8lL00	22 Jul, 2015	3.60.20.10	Assigned
4y8lM00	22 Jul, 2015	3.60.20.10	Assigned
4y8lN00	22 Jul, 2015	3.60.20.10	Assigned
4y8lO00	22 Jul, 2015	3.60.20.10	Assigned
4y8lP00	22 Jul, 2015	3.60.20.10	Assigned
4y8lQ00	22 Jul, 2015	3.60.20.10	Assigned
4y8lR00	22 Jul, 2015	3.60.20.10	Assigned
4y8lS00	22 Jul, 2015	3.60.20.10	Assigned
4y8lT00	22 Jul, 2015	3.60.20.10	Assigned
4y8lU00	22 Jul, 2015	3.60.20.10	Assigned
4y8lV00	22 Jul, 2015	3.60.20.10	Assigned
4y8lW00	22 Jul, 2015	3.60.20.10	Assigned
4y8lX00	22 Jul, 2015	3.60.20.10	Assigned
4y8lY00	22 Jul, 2015	3.60.20.10	Assigned
4y8lZ00	22 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5