PDB Information

PDB4Y6O
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Kinetic and Structural Basis for Acyl-Group Selectivity and NAD(+) Dependence in Sirtuin-Catalyzed Deacylation.
Feldman, J.L., Dittenhafer-Reed, K.E., Kudo, N., Thelen, J.N., Ito, A., Yoshida, M., Denu, J.M.
Biochemistry
HeaderHydrolase/Peptide
Released2015-02-13
Resolution1.600
CATH Insert Date27 Mar, 2016

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 28 Mar, 2016 Chopped
B 28 Mar, 2016 Chopped
C 28 Mar, 2016 Rejected
D 28 Mar, 2016 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4y6oA01 25 Jan, 2017 3.40.50.1220 Assigned
4y6oA02 25 Jan, 2017 3.30.1600.10 Assigned
4y6oB01 25 Jan, 2017 3.40.50.1220 Assigned
4y6oB02 25 Jan, 2017 3.30.1600.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
P01375 TNFA_HUMAN Homo sapiens Tumor necrosis factor
P01375 TNFA_HUMAN Homo sapiens Tumor necrosis factor
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2