PDB 4xv2

PDB Links
Overview

PDB Information

PDB	4XV2
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	RAF inhibitors that evade paradoxical MAPK pathway activation. Zhang, C., Spevak, W., Zhang, Y., Burton, E.A., Ma, Y., Habets, G., Zhang, J., Lin, J., Ewing, T., Matusow, B., Tsang, G., Marimuthu, A., Cho, H., Wu, G., Wang, W., Fong, D., Nguyen, H., Shi, S., Womack, P., Nespi, M., Shellooe, R., Carias, H., Powell, B., Light, E., Sanftner, L., Walters, J., Tsai, J., West, B.L., Visor, G., Rezaei, H., Lin, P.S., Nolop, K., Ibrahim, P.N., Hirth, P., Bollag, G. Nature
Header	Transferase/Transferase Inhibitor
Released	2015-01-26
Resolution	2.500
CATH Insert Date	08 Nov, 2015

PDB Images (7)

Image of CATH 4xv2

4xv2

PDB 4xv2

Image of CATH 4xv2A

4xv2A

PDB Chain 4xv2A

Image of CATH 4xv2B

4xv2B

PDB Chain 4xv2B

Image of CATH 4xv2A01

4xv2A01

CATH Domain 4xv2A01

Image of CATH 4xv2A02

4xv2A02

CATH Domain 4xv2A02

Image of CATH 4xv2B01

4xv2B01

CATH Domain 4xv2B01

Image of CATH 4xv2B02

4xv2B02

CATH Domain 4xv2B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	09 Nov, 2015	Chopped
B	09 Nov, 2015	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4xv2A01	12 Nov, 2015	3.30.200.20	Assigned
4xv2A02	12 Nov, 2015	1.10.510.10	Assigned
4xv2B01	12 Nov, 2015	3.30.200.20	Assigned
4xv2B02	12 Nov, 2015	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf
P15056	BRAF_HUMAN	Homo sapiens	Serine/threonine-protein kinase B-raf