PDB Information

PDB4XRX
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
Wu, F., Jiang, H., Zheng, B., Kogiso, M., Yao, Y., Zhou, C., Li, X.N., Song, Y.
J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2015-01-21
Resolution3.200
CATH Insert Date20 Dec, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Dec, 2015 Chopped
B 21 Dec, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4xrxA00 05 Jan, 2016 3.40.718.10 Assigned
4xrxB00 05 Jan, 2016 3.40.718.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
O75874 IDHC_HUMAN Homo sapiens Isocitrate dehydrogenase [NADP] cytoplasmic
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