PDB 4xrx
PDB Information
PDB | 4XRX |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | Inhibition of Cancer-Associated Mutant Isocitrate Dehydrogenases by 2-Thiohydantoin Compounds.
J.Med.Chem.
|
Header | Oxidoreductase/Oxidoreductase Inhibitor |
Released | 2015-01-21 |
Resolution | 3.200 |
CATH Insert Date | 20 Dec, 2015 |
PDB Images (5)
PDB Prints
PDB Chains (2)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 21 Dec, 2015 | Chopped |
B | 21 Dec, 2015 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4xrxA00 | 05 Jan, 2016 | 3.40.718.10 | Assigned |
4xrxB00 | 05 Jan, 2016 | 3.40.718.10 | Assigned |
UniProtKB Entries (2)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
O75874 | IDHC_HUMAN | Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic |
O75874 | IDHC_HUMAN | Homo sapiens | Isocitrate dehydrogenase [NADP] cytoplasmic |