PDB Information

PDB4XJT
MethodX-RAY DIFFRACTION
Host OrganismPichia
Gene SourceHomo sapiens
Primary Citation
Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38.
Becherer, J.D., Boros, E.E., Carpenter, T.Y., Cowan, D.J., Deaton, D.N., Haffner, C.D., Jeune, M.R., Kaldor, I.W., Poole, J.C., Preugschat, F., Rheault, T.R., Schulte, C.A., Shearer, B.G., Shearer, T.W., Shewchuk, L.M., Smalley, T.L., Stewart, E.L., Stuart, J.D., Ulrich, J.C.
J.Med.Chem.
HeaderHydrolase, Transferase
Released2015-01-09
Resolution2.600
CATH Insert Date06 Sep, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Sep, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4xjtA01 30 Sep, 2015 1.20.82.10 Assigned
4xjtA02 30 Sep, 2015 3.40.50.720 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P28907 CD38_HUMAN Homo sapiens ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
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