PDB 4x7o

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PDB Information

PDB	4X7O
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). Smith, A.L., Andrews, K.L., Beckmann, H., Bellon, S.F., Beltran, P.J., Booker, S., Chen, H., Chung, Y.A., D'Angelo, N.D., Dao, J., Dellamaggiore, K.R., Jaeckel, P., Kendall, R., Labitzke, K., Long, A.M., Materna-Reichelt, S., Mitchell, P., Norman, M.H., Powers, D., Rose, M., Shaffer, P.L., Wu, M.M., Lipford, J.R. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-12-09
Resolution	2.650
CATH Insert Date	28 Jun, 2015

PDB Images (2)

Image of CATH 4x7o

4x7o

PDB 4x7o

Image of CATH 4x7oA

4x7oA

PDB Chain 4x7oA

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Holding pen

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q9NZJ5	E2AK3_HUMAN	Homo sapiens	Eukaryotic translation initiation factor 2-alpha kinase 3