PDB 4x7n

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PDB Information

PDB	4X7N
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of 1H-Pyrazol-3(2H)-ones as Potent and Selective Inhibitors of Protein Kinase R-like Endoplasmic Reticulum Kinase (PERK). Smith, A.L., Andrews, K.L., Beckmann, H., Bellon, S.F., Beltran, P.J., Booker, S., Chen, H., Chung, Y.A., D'Angelo, N.D., Dao, J., Dellamaggiore, K.R., Jaeckel, P., Kendall, R., Labitzke, K., Long, A.M., Materna-Reichelt, S., Mitchell, P., Norman, M.H., Powers, D., Rose, M., Shaffer, P.L., Wu, M.M., Lipford, J.R. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-12-09
Resolution	2.350
CATH Insert Date	28 Jun, 2015

PDB Images (2)

Image of CATH 4x7n

4x7n

PDB 4x7n

Image of CATH 4x7nA

4x7nA

PDB Chain 4x7nA

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	29 Jun, 2015	Domchop review

CATH Domains (0)

Domain ID	Date inserted into CATH	Superfamily	CATH Status

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
Q9NZJ5	E2AK3_HUMAN	Homo sapiens	Eukaryotic translation initiation factor 2-alpha kinase 3