PDB Information

PDB4X2U
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum FcB1/Columbia
Primary Citation
X-ray crystal structures of an orally available aminopeptidase inhibitor, Tosedostat, bound to anti-malarial drug targets PfA-M1 and PfA-M17.
Drinkwater, N., Bamert, R.S., Sivaraman, K.K., Paiardini, A., McGowan, S.
Proteins
HeaderHydrolase/Hydrolase Inhibitor
Released2014-11-27
Resolution1.500
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
4x2uA01 20 Jul, 2015 2.60.40.1730 Assigned
4x2uA02 20 Jul, 2015 3.30.2010.30 Assigned
4x2uA03 20 Jul, 2015 1.10.390.10 Assigned
4x2uA04 20 Jul, 2015 2.60.40.1840 Assigned
4x2uA05 20 Jul, 2015 1.25.50.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O96935 AMP1_PLAFQ Plasmodium falciparum FcB1/Columbia M1 family aminopeptidase
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