PDB 4wy1

PDB Information

PDB4WY1
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of a Series of Efficient, Centrally Efficacious BACE1 Inhibitors through Structure-Based Drug Design.
Butler, C.R., Brodney, M.A., Beck, E.M., Barreiro, G., Nolan, C.E., Pan, F., Vajdos, F., Parris, K., Varghese, A.H., Helal, C.J., Lira, R., Doran, S.D., Riddell, D.R., Buzon, L.M., Dutra, J.K., Martinez-Alsina, L.A., Ogilvie, K., Murray, J.C., Young, J.M., Atchison, K., Robshaw, A., Gonzales, C., Wang, J., Zhang, Y., O'Neill, B.T.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2014-11-14
Resolution1.980
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4wy1A01 22 Jul, 2015 2.40.70.10 Assigned
4wy1A02 22 Jul, 2015 2.40.70.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
CATH-Gene3D is a Global Biodata Core Resource Learn more...