Discovery and in Vivo Evaluation of (S)-N-(1-(7-Fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and Related PI3K delta Inhibitors for Inflammation and Autoimmune Disease.
Cushing, T.D., Hao, X., Shin, Y., Andrews, K., Brown, M., Cardozo, M., Chen, Y., Duquette, J., Fisher, B., Gonzalez-Lopez de Turiso, F., He, X., Henne, K.R., Hu, Y.L., Hungate, R., Johnson, M.G., Kelly, R.C., Lucas, B., McCarter, J.D., McGee, L.R., Medina, J.C., San Miguel, T., Mohn, D., Pattaropong, V., Pettus, L.H., Reichelt, A., Rzasa, R.M., Seganish, J., Tasker, A.S., Wahl, R.C., Wannberg, S., Whittington, D.A., Whoriskey, J., Yu, G., Zalameda, L., Zhang, D., Metz, D.P.
J.Med.Chem.
