PDB Information

PDB4WUY
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
LLY-507, a Cell-active, Potent, and Selective Inhibitor of Protein-lysine Methyltransferase SMYD2.
Nguyen, H., Allali-Hassani, A., Antonysamy, S., Chang, S., Chen, L.H., Curtis, C., Emtage, S., Fan, L., Gheyi, T., Li, F., Liu, S., Martin, J.R., Mendel, D., Olsen, J.B., Pelletier, L., Shatseva, T., Wu, S., Zhang, F.F., Arrowsmith, C.H., Brown, P.J., Campbell, R.M., Garcia, B.A., Barsyte-Lovejoy, D., Mader, M., Vedadi, M.
J.Biol.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-11-04
Resolution1.630
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4wuyA01 20 Jul, 2015 2.170.270.10 Assigned
4wuyA02 20 Jul, 2015 Holding pen
4wuyA03 20 Jul, 2015 1.25.40.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9NRG4 SMYD2_HUMAN Homo sapiens N-lysine methyltransferase SMYD2
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