PDB 4wtu
PDB Information
PDB | 4WTU |
Method | X-RAY DIFFRACTION |
Host Organism | Escherichia coli |
Gene Source | Homo sapiens |
Primary Citation | An Orally Available BACE1 Inhibitor That Affords Robust CNS A beta Reduction without Cardiovascular Liabilities.
Acs Med.Chem.Lett.
|
Header | Hydrolase/Hydrolase Inhibitor |
Released | 2014-10-30 |
Resolution | 1.850 |
CATH Insert Date | 28 Jun, 2015 |
PDB Images (4)
PDB Prints
PDB Chains (1)
Chain ID | Date inserted into CATH | CATH Status |
---|---|---|
A | 29 Jun, 2015 | Chopped |
CATH Domains (2)
Domain ID | Date inserted into CATH | Superfamily | CATH Status |
---|---|---|---|
4wtuA01 | 20 Jul, 2015 | 2.40.70.10 | Assigned |
4wtuA02 | 20 Jul, 2015 | 2.40.70.10 | Assigned |
UniProtKB Entries (1)
Accession | Gene ID | Taxon | Description |
---|---|---|---|
P56817 | BACE1_HUMAN | Homo sapiens | Beta-secretase 1 |