PDB 4wt6

PDB Information

PDB4WT6
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors.
Wu, B., Wang, H.L., Cee, V.J., Lanman, B.A., Nixey, T., Pettus, L., Reed, A.B., Wurz, R.P., Guerrero, N., Sastri, C., Winston, J., Lipford, J.R., Lee, M.R., Mohr, C., Andrews, K.L., Tasker, A.S.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-10-29
Resolution2.300
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4wt6A01 22 Jul, 2015 3.30.200.20 Assigned
4wt6A02 22 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1
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