PDB Information

PDB4WJ7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Basis for the Disruption of the Cerebral Cavernous Malformations 2 (CCM2) Interaction with Krev Interaction Trapped 1 (KRIT1) by Disease-associated Mutations.
Fisher, O.S., Liu, W., Zhang, R., Stiegler, A.L., Ghedia, S., Weber, J.L., Boggon, T.J.
J.Biol.Chem.
HeaderProtein Binding
Released2014-09-29
Resolution2.750
CATH Insert Date04 Jan, 2015

PDB Images (13)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Jan, 2015 Chopped
B 05 Jan, 2015 Chopped
C 05 Jan, 2015 Chopped
D 05 Jan, 2015 Chopped
W 05 Jan, 2015 Rejected
X 05 Jan, 2015 Rejected
Y 05 Jan, 2015 Rejected
Z 05 Jan, 2015 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4wj7A00 20 Mar, 2016 2.30.29.30 Assigned
4wj7B00 20 Mar, 2016 2.30.29.30 Assigned
4wj7C00 20 Mar, 2016 2.30.29.30 Assigned
4wj7D00 20 Mar, 2016 2.30.29.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q9BSQ5 CCM2_HUMAN Homo sapiens Cerebral cavernous malformations 2 protein
Q9BSQ5 CCM2_HUMAN Homo sapiens Cerebral cavernous malformations 2 protein
Q9BSQ5 CCM2_HUMAN Homo sapiens Cerebral cavernous malformations 2 protein
Q9BSQ5 CCM2_HUMAN Homo sapiens Cerebral cavernous malformations 2 protein