PDB 4w6e

PDB Information

PDB4W6E
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology.
Johannes, J.W., Almeida, L., Barlaam, B., Boriack-Sjodin, P.A., Casella, R., Croft, R.A., Dishington, A.P., Gingipalli, L., Gu, C., Hawkins, J.L., Holmes, J.L., Howard, T., Huang, J., Ioannidis, S., Kazmirski, S., Lamb, M.L., McGuire, T.M., Moore, J.E., Ogg, D., Patel, A., Pike, K.G., Pontz, T., Robb, G.R., Su, N., Wang, H., Wu, X., Zhang, H.J., Zhang, Y., Zheng, X., Wang, T.
Acs Med.Chem.Lett.
HeaderTransferase/Inhibitor
Released2014-08-20
Resolution1.950
CATH Insert Date28 Jun, 2015

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
4w6eA00 15 Jul, 2015 3.90.228.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O95271 TNKS1_HUMAN Homo sapiens Poly [ADP-ribose] polymerase tankyrase-1
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