PDB 4v25
PDB Information
| PDB | 4V25 |
| Method | X-RAY DIFFRACTION |
| Host Organism | ESCHERICHIA COLI |
| Gene Source | HOMO SAPIENS |
| Primary Citation | VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells.
Oncotarget
|
| Header | Transferase |
| Released | 2014-10-06 |
| Resolution | 2.600 |
| CATH Insert Date | 14 Dec, 2014 |
PDB Prints
PDB Chains (1)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 15 Dec, 2014 | Chopped |
CATH Domains (2)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4v25A01 | 28 Dec, 2014 | 1.20.140.20 | Assigned |
| 4v25A02 | 28 Dec, 2014 | 3.30.565.10 | Assigned |
UniProtKB Entries (1)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| Q15119 | PDK2_HUMAN | Homo sapiens | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial |
